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Abstract
Animal models for seizures and epilepsy have played a fundamental role in advancing our understanding of basic mechanisms underlying epileptogenesis and have instrumental in the discovery and preclinical development of novel antiepileptic drugs. This paper reviews the invivo models like the electrically induced convulsion (e.g. maximal electroshock, kindling) and chemoconvulsants (e.g. strychnine, pentylenetetrazole, picrotoxin, isoniazid, lithium pilocarpine, yohimbine, bicuculline, 4aminopyridine and penicillin), invitro and genetic model for seizures and epilepsy.
Keywords
epilepsy
animal model
convulsion
antiepileptic drugs
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How to Cite
S, K., K, K., P, M., & S, K. (2013). A REVIEW: ANIMAL MODELS USED IN THE SCREENING OF ANTIEPILEPTIC DRUGS . International Research Journal of Pharmaceutical and Applied Sciences, 3(3), 18-23. Retrieved from https://www.scienztech.org/index.php/irjpas/article/view/470